Vono Lazan Fumarate API

Name	Vono Lazan Fumarate
Chinese name	富马酸沃诺拉赞
Cas Number	881681-01-2
Source	India
Qualifications	-/-/-/-/-

Voronolazan fumarate is a new mechanism of acid inhibitory drug-potassium ion competitive acid blocker (P-CAB). The development company is Takeda Pharmaceutical & Otsuka Pharmaceutical. It was approved for marketing by PMDA in December 2014. In December 2019, it was approved by NMPA for listing. This variety is a new type of potassium ion-competitive acid blocker, which can competitively inhibit the binding of K+ and H+-K+-ATPase during the final step of gastric acid secretion by parietal cells to produce a strong and durable Inhibit the secretion of gastric acid. Compared with the proton pump inhibitor (PPI), P-CAB reversibly binds to the H+/K+-ATPase in a potassium ion competitive manner, thereby quickly inhibiting the secretion of gastric acid. The first dose can achieve the maximum acid suppression effect. . Its brand-new mechanism of action and rapid acid suppression ability pose a market threat to proton pump inhibitors.

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