Rizatriptan Benzoate API

Name	Rizatriptan benzoate
Chinese name	苯甲酸利扎曲普坦
Cas Number	145202-66-0
Source	India
Qualifications	USDMF/-/-/-/-

Rizatriptan benzoate is a selective 5-HT1B/1D receptor agonist developed by Merck, USA, and is the fourth triptan drug to be marketed. Rizatriptan benzoate stimulates the dilated extracerebral and intracranial blood vessels and 5-HT1B/1D on the trigeminal nerve endings during migraine attacks, causing intracranial vasoconstriction and inhibiting the release and transmission of neuropeptides in the trigeminal pain pathway , And play its role in the treatment of migraine. It is better than other triptan drugs in rapid pain relief. Compared with naratriptan, rizatriptan benzoate is more effective in the early treatment of pain onset. The migraine relief rate of oral rizatriptan benzoate 5mg is higher than that of sumatriptan 100mg, the first-generation pantan drug, and the side effects are lighter than sumatriptan. Rizatriptan benzoate has obvious curative effect in the treatment of migraine with good safety and tolerability. It is superior to the similar drug zolmitriptan in the treatment of acute migraine. It has high clinical application value and is a great Drugs with market prospects.

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