Estriol API

Name	Estriol
Chinese name	雌三醇
Cas Number	50-27-1
Source	Europe
Qualifications	USDMF/CEP/-/-/-

Estriol is a metabolite of estradiol in the body. It is a natural estrogen mainly found in urine. Its oral estrogenic activity is about 6 times that of estrone. Animal experiments show that estriol has a stronger effect on vaginal epithelial keratinization than estradiol, which can promote vaginal epithelial hyperplasia, superficial cell keratinization, mucosal angiogenesis and vaginal epithelial injury healing; at the same time, estriol can enhance cervical cell function. Proliferate cervical muscle fibers, increase cervical elasticity and flexibility. In addition, estriol has a feedback inhibitory effect on the hypothalamus and pituitary gland, but does not inhibit ovulation, and only has a significant effect on the corpus luteum. Therefore, it can be used as an auxiliary drug for mid-term labor induction and artificial abortion and the treatment of various menstrual diseases. The latest clinical studies have shown that estriol ointment combined with live Lactobacillus capsules has little effect on serum sex hormone levels in elderly patients with vaginitis. The patient has high adaptability, significant curative effect and low recurrence rate, which is worthy of clinical application and promotion.

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