Foscarnet Sodium API

Name	Foscarnet Sodium
Chinese name	膦甲酸钠
Cas Number	63585-09-1
Source	India
Qualifications	USDMF/-/-/-/-

Foscarnet sodium is a high-efficiency, low-toxicity and broad-spectrum non-nucleoside antiviral drug. It can inhibit viral RNA and DNA polymerase, and inhibit HIV reverse transcriptase, and has a good effect on cytomegalovirus and herpes simplex virus infection. Foscarnet sodium is an organic analogue of inorganic pyrophosphate. Without affecting the concentration of cell DNA polymerase, foscarnet sodium selectively inhibits the pyrophosphate binding site of virus-specific DNA polymerase, thereby showing resistance Viral activity. Foscarnet sodium is the second drug approved by the FDA for the treatment of cytomegalovirus retinitis in patients with AIDS. It has been listed in the British Pharmacopoeia and has received wide attention. The study pointed out that in the practice of clinical treatment of AIDS patients with herpes zoster, compared with acyclovir treatment, the effect of treatment with foscarnet sodium is significant, and it is an ideal choice for clinical treatment of AIDS patients with herpes zoster. In 2016, the market size of antiviral drugs in public hospitals and retail pharmacies in key cities in China was 2.424 billion yuan and 1.419 billion yuan, respectively. The amount of antiviral drugs used in public hospitals in key cities increased by 11.88% year-on-year.

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