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Active Pharmaceutical Ingredient
Benserazide API

Benserazide API

CAS:322-35-0
Source:Europe
Qualifications:-/-/-/-/-

Product Details

NameBenserazide
Chinese name苄丝肼
Cas Number322-35-0
SourceEurope
Qualifications-/-/-/-/-



Benserazide is a peripheral dopa decarboxylase inhibitor, and it forms a compound preparation dopasizide with levodopa. Its effect is the same as that of levodopa, but because benserazide is a decarboxylase inhibitor, it can inhibit levodopa outside the brain. Decarboxylation increases the amount of levodopa in the brain, so it can reduce the amount of levodopa, thereby reducing the adverse reactions caused by it and enhancing the patient's tolerance. After oral administration, the absorption is fast, and the plasma protein binding rate is 58%. The latest research found that benserazide may inhibit the expression of related pro-inflammatory cytokines in HUVECs caused by LPS by inhibiting the activation and nuclear translocation of the AKT/NF-κB pathway and p38 MAPK partial pathways. So as to play the role of anti-atherosclerosis. The raw materials are produced in Europe, imported high-quality raw materials, supplied by well-known manufacturers, good quality, complete qualifications




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