Sleppug API

Name	Sleppug
Chinese name	司来帕格
Cas Number	475086-01-2
Source	India
Qualifications	USDMF/-/-/-/-

It is an effective, highly selective and long-acting non-prostaglandin prostacyclin receptor (IP receptor) agonist that can improve the endothelium-dependent relaxation of injured pulmonary artery and may inhibit the proliferation of human lung smooth muscle cells. Thickening of pulmonary vessel walls. Compared with the prostacyclin drugs that are already on the market for the treatment of pulmonary hypertension, this product is the first oral preparation that can improve patient compliance. This product is convenient to use, avoids injection site reactions of intravenous administration, and avoids throat irritation and coughing of inhaled dosage forms. As a clinically urgently needed variety, selepag tablets were included in the priority review procedure by the China National Medical Products Administration to speed up review and approval. On December 7, 2018, the National Medical Products Administration of China approved the import registration of this product for the treatment of pulmonary hypertension to delay disease progression and reduce the risk of hospitalization due to pulmonary hypertension.

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