Fosapidem Dimethyl Meglumine API

Name	Fosapidem dimethyl meglumine
Chinese name	福沙吡坦二甲葡胺
Cas Number	265121-04-8
Source	India
Qualifications	USDMF/-/-/-/-

Fosapitan Dimeglumine for injection was developed by Merck and was approved for marketing in the United States in 2008. At present, this product has been marketed in the UK, Japan, and many European countries, but has not yet been marketed in my country. This product is a prodrug of aprepitant oral preparations, which is rapidly transformed into aprepitant in the body after injection, and is another NK-1 receptor antagonist currently used in clinical practice after aprepitant Agent. Fosapitan dimethyl meglumine and aprepitant belong to a selective high-affinity receptor blocker called human substance P/neurokinin 1 (NK-1), mainly by blocking nausea and vomiting signals in the brain The novel mechanism of action comes into play. Fosaprepitant is a good supplement for oral aprepitant, because it can effectively prevent chemotherapy-induced delayed nausea and vomiting, make up for the deficiency of 5-HT3 receptor antagonists, and is recommended by major global guidelines And recognized by international authoritative academic organizations, it has become a hot antiemetic product.

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